Complex Loading of the Intervertebral Disc

The main focus of this SNF-funded project was to look at the biological response of the IVD under dynamic torsion and compression loading (Jan 2009- Dec 2012). The initial aims of this project were to look into the effects of compression and torsion on the metabolism of intervertebral discs, and then to generate a model of disc degeneration by applying hyper-physiological complex loading consisting of dynamic torsion and compression. The SNF project was very successful and future research is planned to focus on the importance of resting in loading regimes and the importance of torsion and biology seemed generally overlooked in the biomechanical literature. Our recently proposed disc degeneration model can be used to investigate the importance of resting and for investigating how torque may cause cell death in the center of the disc.