Musculoskeletal Biomechanics

Research Profile

The Musculoskeletal Biomechanics Group completed the transition related to the appointment of Prof. Philippe Zysset in the fall 2011. With the efficient support of the ISTB and the university and canton of Bern a novel biomechanics laboratory was inaugurated in early June 2012 in the presence of colleagues and partners. The equipment of the tissue preparation room was extended, the servo-hydraulic material testing system was moved to the basement and a state-of-the-art depth-sensing nano-indentation system was installed to investigate the post-yield properties of bone extracellular matrix. All the lab procedures for storage, preparation and testing of human and animal tissue were successfully updated.

Motivated by the prevention, diagnosis, treatment and follow-up of bone fractures, the research of the group focuses on multi-scale structure-function relationships of bone tissue from the extracellular matrix to the organ level. A combined theoretical, experimental, and numerical approach is pursued to model, validate and simulate the mechanical behavior of human bone in the course of growth, aging, disease and treatment. Research interests range from the elucidation of lamellar bone theory up to failure mechanisms of the proximal femur.